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Article

A unified framework for multi-locus association analysis of both common and rare variants.

BMC genomics - 31 Jan 2011

Shriner Daniel, Vaughan Laura Kelly

Abstract excerpt

BACKGROUND: Common, complex diseases are hypothesized to result from a combination of common and rare genetic variants. We developed a unified framework for the joint association testing of both types of variants. Within the framework, we developed a union-intersection test suitable for genome-wide analysis of single nucleotide polymorphisms (SNPs), candidate gene data, as well as medical sequencing data. The...

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Identifiers

PMID: 21281506
DOI: 10.1186/1471-2164-12-89
PMCID: PMC3040731

Genes

GAK
NGLY1
SYN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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