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Article

A multi-SNP association test for complex diseases incorporating an optimal P-value threshold algorithm in nuclear families.

BMC genomics - 15 May 2015

Wang Yi-Ting, Sung Pei-Yuan, Lin Peng-Lin, Yu Ya-Wen, Chung Ren-Hua

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have become a common approach to identifying single nucleotide polymorphisms (SNPs) associated with complex diseases. As complex diseases are caused by the joint effects of multiple genes, while the effect of individual gene or SNP is modest, a m...

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PMID: 25975968
DOI: 10.1186/s12864-015-1620-3
PMCID: PMC4433014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25975968-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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