Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-ancestry multi-trait analysis reveals shared genetics across major psychiatric disorders and Alzheimer's disease.

Translational psychiatry - 26 Jun 2026

Zheng Xin, Feng Hongye, Ren Lijie, Zhang Youcheng

Abstract excerpt

The clinical overlap between major psychiatric disorders (MPDs) and Alzheimer's disease (AD) implicates complex shared etiology. Previous studies demonstrated that both diseases are genetically complex and highly heritable, suggesting that more endeavors are necessary to be made from the very bottom to understand their genetic basis. With the advance of post-genomic analysis, multi-ancestry meta-analysis allows...

Read the complete abstract on PubMed

Topics

Humans
Alzheimer Disease
Genetic Predisposition to Disease
Genome-Wide Association Study
Major Depressive Disorder
Mental Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Schizophrenia

White People

East Asian People

Black or African American

Hispanic or Latino

Source

Open in PubMed Open full text

Identifiers

PMID: 42362520
DOI: 10.1038/s41398-026-04213-0
PMCID: PMC13572366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-ancestry multi-trait analysis reveals shared genetics across major psychiatric disorders and Alzheimer's disease.PMID 42362520Read ↗

Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s DiseaseSemantic proximity Read ↗

Shared genetic architecture between Alzheimer's disease and psychiatric disorders revealed by multi-trait genome-wide analyses.Semantic proximity Read ↗

Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease.Semantic proximity Read ↗

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.Semantic proximity Read ↗

Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.Semantic proximity Read ↗

A Genome-wide Association Study of Alzheimer’s Disease and Dementia in a Large Multi-ancestry Military Cohort Identifies Many New Dementia-Associated LociSemantic proximity Read ↗

Shared genetic architecture across psychiatric disorders.Semantic proximity Read ↗

Statistical examination of shared loci in neuropsychiatric diseases using genome-wide association study summary statistics.Semantic proximity Read ↗

Comprehensive adjudication identifies 111 high-confidence loci for Alzheimer's disease and related dementiasSemantic proximity Read ↗

Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits.Semantic proximity Read ↗

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies<i>LRRC4C, LHX5-AS1</i>and nominates ancestry-specific loci<i>PTPRK</i>,<i>GRB14</i>, and<i>KIAA0825</i>as novel risk loci for Alzheimer’s disease: the Alzheimer’s Disease Genetics ConsortiumSemantic proximity Read ↗

Multi-ancestry studies in multi-omics of Alzheimer's disease: Recent insights and future directions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.