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A genome-wide cross-trait analysis reveals shared genetic architecture between essential tremor and Parkinson’s disease

2026-08-20

Abstract excerpt

<title>Abstract</title> <p> Background Essential tremor (ET) and Parkinson’s disease (PD) have overlapping clinical features, but the biological basis of their shared liability remains unclear. Methods We integrated genome-wide association study summary statistics using genome-wide and annotation-specific genetic-correlation analyses, cross-phenotype association, fine-mapping, colocalization, gene-based and fu...

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Literature Corpus work
9e6ccf8e-543d-5cbc-a610-6cfd15a7130c
DOI
10.21203/rs.3.rs-10671175/v1
Open publication

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A genome-wide cross-trait analysis reveals shared genetic architecture between essential tremor and Parkinson’s diseaseDOI 10.21203/rs.3.rs-10671175/v1
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