Differential up-regulation of H-2D versus H-2K class I major histocompatibility expression by interferon-gamma: evidence against a trans-acting allele-specific factor.

Abstract excerpt

Previous investigation described a unique differential phenotype for the murine T-cell tumor AKR SL3 with regard to augmentation of class I major histocompatibility complex antigen expression by interferon-gamma (IFN-gamma). Dk expression was increased by IFN-gamma as expected, but Kk expression remained at constitutive levels, despite treatment with a range of doses and times of exposure to IFN-gamma. Analysis...

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