Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells.

Cancer research - 1 Mar 1990

Chen P W, Kaba D S, Ananthaswamy H N

Abstract excerpt

We used somatic cell hybridization to determine whether the regressor phenotype exhibited by UV-induced murine tumors was dominant or recessive and whether this technique could confer immunogenic properties on nonimmunogenic syngeneic tumors. We transfected a highly antigenic UV-induced C3H mouse tumor cell line (UV-2240) with the plasmid pSV2-neo and selected G418-resistant clones. The resulting cell line was...

Topics

Animals
Antigens, Neoplasm
Cross Reactions
Female
Fibrosarcoma
Graft Rejection
Histocompatibility Antigens
Hybridization, Genetic
Immune Tolerance
Mice
Mice, Inbred C3H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Neoplasm Regression, Spontaneous

Neoplasm Transplantation

Neoplasms, Radiation-Induced

Phenotype

Specific Pathogen-Free Organisms

T-Lymphocytes, Cytotoxic

Source

Open in PubMed

Identifiers

PMID: 2137370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2137370-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune response to somatic cell hybrids between ultraviolet radiation-induced regressor and spontaneous progressor C3H mouse tumor cells.PMID 2137370Read ↗

Immune response to progressor variants derived from transfection of an ultraviolet radiation-induced C3H mouse regressor tumor cell line with activated Harvey-ras oncogene.Semantic proximity Read ↗

Resistance of Ha-ras oncogene-induced progressor tumor variants to tumor necrosis factor and interferon-gamma.Semantic proximity Read ↗

Radiation-resistant and radiation-sensitive forms of host resistance to polyomavirus.Semantic proximity Read ↗

Deregulated c-myc expression is insufficient for emergence of the tumorigenic phenotype in malignancy-suppressed intratypic T-cell lymphoma hybrids: an in vitro model for multistep lymphomagenesis.Semantic proximity Read ↗

Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma.Semantic proximity Read ↗

Heterogeneity of MHC-class-I antigens in clones of methylcholanthrene-induced tumors. Implications for local growth and metastasis.Semantic proximity Read ↗

Susceptibility to tumors induced by polyoma virus is conferred by an endogenous mouse mammary tumor virus superantigen.Semantic proximity Read ↗

In vivo acquired mechanisms of tumor cells local defense against the host innate immunity effectors: implication in specific antitumor immunity.Semantic proximity Read ↗

Intrachromosomal recombination between well-separated, homologous sequences in mammalian cells.Semantic proximity Read ↗

Clonal deletion of self-Mls-reactive thymocytes at the early stage in H-2-compatible but Mls-disparate radiation chimeras.Semantic proximity Read ↗

The H-ras oncogene regulates expression of 70- and 45-kDa cell-surface molecules whose expression correlates with tumor-cell immunogenicity.Semantic proximity Read ↗

Dominant-negative p53 can restore tumorigenicity of L-929 cells in immunocompetent mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.