Article
Immune escape phenotype of HPV16-associated tumours: MHC class I expression changes during progression and therapy.
International journal of oncology - 1 Feb 2005
Mikysková Romana, Bubeník Jan, Vonka Vladimír, Smahel Michal, Indrova Marie, Bieblová Jana, Símová Jana, Jandlová Tána
Abstract excerpt
Malignant transformation of somatic cells followed by selection of the transformed cell populations can give rise to tumours that display an immune escape phenotype, MHC class I deficient neoplasms. Experiments were designed to examine whether the immune escape phenotype of HPV16-associated tumours is stable or whether the MHC class I expression can change during tumour progression and therapy. It has been found...
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