Article
Hemopoietic histocompatibility (Hh-1) phenotype and the regulation of its expression.
Immunogenetics - 1 Jan 1992
Kaminsky S G, Yoshida M A, Milisauskas V K, Nakamura I
Abstract excerpt
Hybrid resistance (HR) is primarily controlled by the genes of the Hemopoietic histocompatibility-1 (Hh-1) locus within the H-2 complex. HR is a consequence of the Hh-1-controlled target determinants in homozygous parental strain mice and their absence in heterozygous F1 hybrid mice. To examine the mechanism that controls the Hh-1 phenotype, three independent clones of somatic cell hybrids between parental lines...
Topics
- Animals
- Blotting, Southern
- Chromosome Mapping
- Female
- Gene Expression Regulation
- H-2 Antigens
- Histocompatibility Antigens
- Hybrid Cells
- Killer Cells, Natural
- Mice
- Mice, Inbred C3H