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Article

Characterization of a novel IRF-1-deficient mutant cell line.

Immunogenetics - 1 Jan 1994

Lim S P, Hui K M

Abstract excerpt

The transcriptional activation of the major histocompatibility complex (MHC) class I genes by both type I (alpha/beta) and II (gamma) interferons (IFNs) has been extensively studied, and it has been shown that the upregulation of several DNA-binding proteins is critical for this process. In our laboratory, we introduced the mouse H-2Kb gene into the AKR mouse leukaemia cell line K36.16 to effect the generation of...

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Identifiers

PMID: 7506233
DOI: 10.1007/BF00241257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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