Characterization of a novel IRF-1-deficient mutant cell line.

doi:10.1007/BF00241257

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Article

Characterization of a novel IRF-1-deficient mutant cell line.

Immunogenetics - 1 Jan 1994

Lim S P, Hui K M

Abstract excerpt

The transcriptional activation of the major histocompatibility complex (MHC) class I genes by both type I (alpha/beta) and II (gamma) interferons (IFNs) has been extensively studied, and it has been shown that the upregulation of several DNA-binding proteins is critical for this process. In our l...

Topics

Animals
Base Sequence
Cell Division
Clone Cells
Consensus Sequence
DNA-Binding Proteins
Gene Expression Regulation, Neoplastic
H-2 Antigens
Histocompatibility Antigens Class I
Interferon Regulatory Factor-1
Interferon Regulatory Factor-2
Interferons
Mice
Mice, Inbred AKR
Molecular Sequence Data
Mutation
Phosphoproteins
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 7506233
DOI: 10.1007/BF00241257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7506233-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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