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Article

BDNF-restricted knockout mice as an animal model for aggression.

Genes, brain, and behavior - 1 Apr 2011

Ito W, Chehab M, Thakur S, Li J, Morozov A

Abstract excerpt

Mice with global deletion of one brain-derived neurotrophic factor (BDNF) allele or with forebrain-restricted deletion of both alleles show elevated aggression, but this phenotype is accompanied by other behavioral changes, including increases in anxiety and deficits in cognition. Here we performed behavioral characterization of conditional BDNF knockout mice generated using a Cre recombinase driver line,...

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Source

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Identifiers

PMID: 21255268
DOI: 10.1111/j.1601-183X.2010.00676.x
PMCID: PMC3080454

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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