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Article

Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice.

Neuroscience - 1 Jan 2003

Gorski J A, Balogh S A, Wehner J M, Jones K R

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) participates in synaptic plasticity and the adaptive changes in the strength of communication between neurons thought to underlie aspects of behavioral adaptation. By selectively deleting BDNF from the forebrain of mice using the Cre site-specific DNA recombinase, we were able to study the requirements for BDNF in behaviors such as learning and anxiety. Early-onset...

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Source

Identifiers

PMID: 14521993
DOI: 10.1016/s0306-4522(03)00426-3

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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