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Article

Envelope stress is a trigger of CRISPR RNA-mediated DNA silencing in Escherichia coli.

Molecular microbiology - 1 Feb 2011

Perez-Rodriguez Ritsdeliz, Haitjema Charles, Huang Qingqiu, Nam Ki Hyun, Bernardis Sarah, Ke Ailong, DeLisa Matthew P

Abstract excerpt

A widespread feature in the genomes of most bacteria and archaea is an array of clustered, regularly interspaced short palindromic repeats (CRISPRs) that, together with a group of CRISPR-associated (Cas) proteins, mediate immunity against invasive nucleic acids such as plasmids and viruses. Here, the CRISPR-Cas system was activated in cells expressing a plasmid-encoded protein that was targeted to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21255106
DOI: 10.1111/j.1365-2958.2010.07482.x
PMCID: PMC3040579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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