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Discovery of new type I toxin–antitoxin systems adjacent to CRISPR arrays in Clostridium difficile

12 Feb 2018

Abstract excerpt

Clostridium difficile, a major human enteropathogen, must cope with foreign DNA invaders and multiple stress factors inside the host. We have recently provided an experimental evidence of defensive function of the C. difficile CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) system important for its survival within phage-rich gut communities. Here, we describe the...

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PMID: 29529286
DOI: 10.1093/nar/gky124

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