Article
HLA-Bw4-B*57 and Cw*18 alleles are associated with plasma viral load modulation in HIV-1 infected individuals in Salvador, Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Silva Edinete Melo da, Acosta Angelina Xavier, Santos Eduardo José Melo, Netto Eduardo Martins, Lemaire Denise Carneiro, Oliveira Adriano Silva, Barbosa Carolina Matos, Bendicho Maria Teresita, Galvão-Castro Bernardo, Brites Carlos
Abstract excerpt
UNLABELLED: Host genetic factors play an important role in mediating resistance to HIV-1 infection and may modify the course of infection. HLA-B alleles (Bw4 epitope; B*27 and B*57) as well as killer cell immunoglobulin-like receptors have been associated with slow progression of HIV-1 infection. OBJECTIVE: To evaluate the association between serological epitopes HLA-Bw4 and HLA-Bw6 and prognostic markers in...
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