Article
High Frequency of Human Leukocyte Antigen-B*57:01 Allele Carriers among HIV-Infected Patients in Serbia.
Intervirology - 1 Jan 2017
Siljic Marina, Salemovic Dubravka, Cirkovic Valentina, Pesic-Pavlovic Ivana, Todorovic Marija, Ranin Jovan, Dragovic Gordana, Jevtovic Djordje, Stanojevic Maja
Abstract excerpt
Abacavir is an effective antiretroviral drug and one of the most commonly used nucleoside reverse transcriptase inhibitors in Serbia. А percentage of the treated patients experience a potentially life-threatening hypersensitivity reaction, which was shown to be associated with the presence of the class I MHC allele, HLA-B*57:01; hence genotyping for HLA-B*57:01 prior to starting abacavir is nowadays recommended...
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