Article
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.
Proceedings of the National Academy of Sciences of the United States of America - 24 Apr 2001
Flores-Villanueva P O, Yunis E J, Delgado J C, Vittinghoff E, Buchbinder S, Leung J Y, Uglialoro A M, Clavijo O P, Rosenberg E S, Kalams S A, Braun J D, Boswell S L, Walker B D, Goldfeld A E
Abstract excerpt
Certain HLA-B antigens have been associated with lack of progression to AIDS. HLA-B alleles can be divided into two mutually exclusive groups based on the expression of the molecular epitopes HLA-Bw4 and HLA-Bw6. Notably, in addition to its role in presenting viral peptides for immune recognition...
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