Article
Functionally active HLA-G polymorphisms are associated with the risk of heterosexual HIV-1 infection in African women.
AIDS (London, England) - 20 Feb 2004
Matte Claudine, Lajoie Julie, Lacaille Julie, Zijenah Lynn S, Ward Brian J, Roger Michel
Abstract excerpt
BACKGROUND: Heterosexual transmission of HIV-1 is the major route of infection worldwide. HLA-G molecules are involved in the inhibition of cell-mediated immune responses and could permit or even promote the propagation of infection in the female reproductive tract. OBJECTIVE: To examine whether HLA-G genetic variants are associated with the risk of heterosexual HIV-1 infection. METHODS: HLA-G polymorphism in DNA...
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