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Article

Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

AIDS (London, England) - 5 Dec 2003

Altfeld Marcus, Addo Marylyn M, Rosenberg Eric S, Hecht Frederick M, Lee Paul K, Vogel Martin, Yu Xu G, Draenert Rika, Johnston Mary N, Strick Daryld, Allen Todd M, Feeney Margaret E, Kahn James O, Sekaly Rafick P, Levy Jay A, Rockstroh Jürgen K, Goulder Philip J, Walker Bruce D

Abstract excerpt

BACKGROUND: HLA-B57, as well as cytotoxic T-lymphocyte (CTL) responses restricted by this allele, have been strongly associated with long-term non-progressive chronic HIV-1 infection. However, their impact on viral replication during acute HIV-1 infection is not known. METHODS: Clinical and immunological parameters during acute and early HIV-1 infection in individuals expressing HLA-B57 were assessed....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to Genes, MHC Class I

Share to HLA-B Antigens

Share to Immunodominant Epitopes

Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 14685052
DOI: 10.1097/00002030-200312050-00005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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