Article
[FMS-like tyrosine kinase 3 gene mutation in acute myeloid leukemia detected by denaturing PAGE and its clinical significance].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2010
Ma Liang, Zhong Ming-Hua, Feng Dai-Rong, Long Hong, Shen Jun, Ma Yi-Gai, Huang Shang-Zhi
Abstract excerpt
The aim of this study was to analyze the frequency of flt3 length mutation (flt3-LM) in de novo acute myeloid leukemia patients and the relationship between flt3-LM and chromosome alterations, FAB subgroups, as well as efficiency of therapy. Genomic DNA was amplified by PCR; 2% agarose gel or 8%...
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