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Article

[Correlation of Fms-like tyrosine kinase 3 (FLT3) gene expression to FLT3/internal tandem duplication mutation in peripheral blood of acute myeloid leukemia.].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Jun 2009

Xu Bing, Shi Peng-Chang, Song Xiao-Yan, Tang Jia-Hong, Zhou Shu-Yun

Abstract excerpt

BACKGROUND AND OBJECTIVE: Fms-like tyrosine kinase 3 internal tandem duplication (FLT3/ITD) is associated with an unfavorable prognosis in acute myeloid leukemia (AML). However, the role of FLT3 expression as well as its correlation to FLT3/ITD has not sufficiently studied. This study was to evaluate the relationship between FLT3 gene expression and FLT3/ITD mutation in patients with de novo AML. METHODS: FLT3...

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Identifiers

PMID: 19635202

Genes

FLT3

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