Article
[Detection and clinical significance of FLT3-ITD gene mutation in patients with acute myeloid leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2012
Xu Yuan-Yuan, Gao Li, Ding Yi, Sun Jun-Zhong, Wang Nan, Wang Li-Li, Yu Li
Abstract excerpt
This study was aimed to evaluate the prevalence of FT3-ITD mutation in patients with acute myeloid leukemia (AML) and its significance for prognosis. The bone marrow of 216 patients with AML were detected by using PCR and R-banding methods. On basis of patients' clinical data the clinical feature and prognosis were analyzed. The results showed that in 216 AML patients incidence of FLT3-ITD mutation was 20.83%....
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