Article
[Analysis of Flt-3 expression and Flt-3/ITD mutation in acute myeloid leukemia cells].
Zhongguo shi yan xue ye xue za zhi - 1 Jun 2006
Wang Ya-Lun, Wang Tong, Xu Feng, Gang Yan, Wang Jie
Abstract excerpt
This study was aimed to explore the relationship between Flt-3 expression, Flt-3/ITD mutation in acute leukemia (AL) cell line and pathogenesis of AL, especially AML. The Flt-3 expression and Flt-3/ITD mutation were detected by RT-PCR and sequencing method in 82 leukemia cell lines including 20 AML, 57 ALL and 5 CML cell lines. The results indicated that positive results of Flt-3 expression were obtained in 48...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
