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[FMS-like tyrosine kinase 3 gene mutations in acute myeloid leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Oct 2009

Han Yang-Li, Zhang Su-Jiang, Qiao Chun, Dai Dan, Sun Xue-Mei, Xu Yan-Li, Qian Si-Xuan, Xu Wei, Wang Ji-Shi, Li Jian-Yong

Abstract excerpt

This study was aimed to investigate the frequency of FMS-like tyrosine kinase 3 (FLT3) mutations including internal tandem duplication (ITD) mutation of juxtamembrane region and point mutation of the second tyrosine kinase domain (TKD) in acute myeloid leukemia (AML) patients and its clinical significance. The ITD mutation in FLT3 exon 14, 15 of bone marrow mononuclear cells was detected by genomic DNA-PCR, the...

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Source

Identifiers

PMID: 19840437

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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