Article
[FLT3 Gene Mutations in Acute Myeloid Leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2015
Ye Li, Ji Meng-Meng, Sun Zi-Min
Abstract excerpt
OBJECTIVE: This study was aimed to detect the FLT3 gene mutation in patients with de-novo acute myeloid leukemia (AML), and to investigate its prognostic value and clinical significance. METHODS: Polymerase chain reaction (PCR) was used to detect FLT3 gene mutation, in bone marrow samples of 54 patients with de novo AML. RESULTS: The incidence of FLT3-ITD mutation in 54 de-novo AML patients was 22.22%, 10 out of...
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