Article
[FLT3 mutation in patients with acute lymphoblastic leukemia and its clinical significance].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Oct 2009
Zhao Xin, Tang Ke-Jing, Tian Zheng, Chen Li-Ping, Mi Ying-Chang, Wang Jian-Xiang
Abstract excerpt
OBJECTIVE: To investigate fms-like tyrosine kinase 3 (FLT3) mutation in patients with acute lymphoblastic leukemia (ALL) and its clinical significance. METHODS: FLT3 mutation-internal tandem duplication (FLT3-ITD) and FLT3 mutation in the tyrosine kinase domain (FLT3-TKD) were detected using polymerase chain reaction (PCR) in the genomic DNA of 61 ALL patients and 7 healthy volunteers (as reference group). The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
