Article
[Detection of FLT3 gene and FLT3/ITD gene mutation in chronic myeloid leukemia and its significance].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Oct 2004
Xu Bing, Tian Hong, Zhou Shu-Yun
Abstract excerpt
BACKGROUND & OBJECTIVE: Fms-like tyrosine kinase 3 (FLT3)gene abnormal expression could be detected in most of acute myeloid leukemia (AML)patients, and 20%-30% of them have FLT3/ITD gene mutation which indicate poor prognosis. This study was to detect FLT3 gene expression, and FLT3/ITD gene mutation in chronic myeloid leukemia (CML)patients, and analyze their relationships with prognosis. METHODS: Polymerase...
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