Article
[Detection of FLT3 gene mutation in hematologic malignancies and its clinical significance].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2007
Liu Hong, Yu Hong, Jia Hong-Ying, Zhang Wen, Guo Cheng-Jie
Abstract excerpt
To study the FLT3 gene expression and its internal tandem duplication in hematologic malignancies and its clinical significance, polymerase chain reaction (PCR) and DNA sequencing were used to detect the FLT3/ITD mutation in blast cells of bone marrow from 86 patients with hematologic malignancies, including 32 cases of acute myeoloid leukemia (AML), 18 cases of acute lymphoblastic leukemia (ALL), 2 cases of...
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