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[Correlation of FLT3 gene expression level and internal tandem duplication mutation in acute myeloid leukemia and its clinical significance].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Nov 2008

Wang Yun-gui, Liu Xu-hui, Liang Yi, Jin Jie

Abstract excerpt

OBJECTIVE: To evaluate the prevalence of FLT3 gene expression and internal tandem duplication (ITD) mutation in acute myeloid leukemia (AML) patients and its clinical significance. METHODS: The expression level of FLT3 mRNA was detected with real-time quantitative RT-PCR (RQ-PCR) technique in 152 bone marrow samples from 129 AML patients. The ITD of the FLT3 gene (FLT3/ITD) was detected in 75 de novo AML patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19176010

Genes

FLT3

Provenance

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