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Article

Temperature-sensitive DNA mutant of Chinese hamster ovary cells with a thermolabile ribonucleotide reductase activity.

Molecular and cellular biology - 1 Nov 1990

Wojcik B E, Dermody J J, Ozer H L, Mun B, Mathews C K

Abstract excerpt

JB3-B is a Chinese hamster ovary cell mutant previously shown to be temperature sensitive for DNA replication (J. J. Dermody, B. E. Wojcik, H. Du, and H. L. Ozer, Mol. Cell. Biol. 6:4594-4601, 1986). It was chosen for detailed study because of its novel property of inhibiting both polyomavirus an...

Topics

Animals
Cell Division
Cell Line
Cell Nucleus
Cricetinae
Cricetulus
DNA
DNA Replication
Deoxyribonucleotides
Enzyme Stability
Female
Kinetics
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovary

Ribonucleotide Reductases

Temperature

Thermodynamics

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2233712
DOI: 10.1128/mcb.10.11.5688-5699.1990
PMCID: PMC361336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2233712-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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