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Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells.

Radiation research - 1 Jul 1992

Chang W P, Little J B

Abstract excerpt

A persistently reduced cloning efficiency occurs in many of the cloned progeny of Chinese hamster ovary (CHO) cells surviving X irradiation, a stable phenotype we have previously termed delayed reproductive death (Int. J. Radiat. Biol. 60, 483-496, 1991). We now report that this phenotype is also induced by the alkylating agent ethyl methanesulfonate (EMS), but not by irradiation with ultraviolet light. The...

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PMID: 1626049

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Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells.PMID 1626049Read ↗

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Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells.Semantic proximity Read ↗

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