Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-lambda serum levels in hepatitis C.

Journal of hepatology - 1 May 2011

Langhans Bettina, Kupfer Bernd, Braunschweiger Ingrid, Arndt Simone, Schulte Wibke, Nischalke Hans Dieter, Nattermann Jacob, Oldenburg Johannes, Sauerbruch Tilman, Spengler Ulrich

Abstract excerpt

BACKGROUND & AIMS: Dendritic cells (DCs) trigger adaptive immune responses and are an important source of antiviral cytokines. In hepatitis C virus (HCV) infection DC function is markedly impaired. Thus far, studies have focused on types I and II interferon (IFN). We studied IFN-lambda1 (IL-29) and IFN-lambda2/3 (IL-28A/B) serum levels in patients with different outcomes of HCV infection. METHODS: IFN-lambdas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferons

Share to Interleukins

Share to Tetraspanin 28

Share to Toll-Like Receptor 2

Share to Viral Envelope Proteins

Share to Viral Nonstructural Proteins

Source

Identifiers

PMID: 21145813
DOI: 10.1016/j.jhep.2010.08.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-lambda serum levels in hepatitis C.PMID 21145813Read ↗

Lambda interferon serum levels in patients with chronic hepatitis C virus infection according to their response to therapy with pegylated interferon and ribavirin.Semantic proximity Read ↗

The Role of Interferon-&#x03BB; Locus Polymorphisms in Hepatitis C and Other Infectious DiseasesSemantic proximity Read ↗

Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.Semantic proximity Read ↗

λ‐Interferons and the single nucleotide polymorphisms: A milestone to tailor‐made therapy for chronic hepatitis CSemantic proximity Read ↗

Investigation into the role of novel interferon lambdas in the treatment of viral disease, primarily hepatitis CSemantic proximity Read ↗

Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus.Semantic proximity Read ↗

Dendritic cells in hepatitis C virus infection: key players in the IFNL3-genotype response.Semantic proximity Read ↗

Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection.Semantic proximity Read ↗

Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection.Semantic proximity Read ↗

IFN-Alpha receptor-1 upregulation in PBMC from HCV naïve patients carrying cc genotype. possible role of IFN-lambda.Semantic proximity Read ↗

Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.Semantic proximity Read ↗

Impaired induction of interleukin 28B and expression of interferon λ 4 associated with nonresponse to interferon-based therapy in chronic hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.