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Article

Investigation into the role of novel interferon lambdas in the treatment of viral disease, primarily hepatitis C

2012-01-01

Abstract excerpt

Interferon lambdas (IFNλs), termed IFN-λ1, IFN-λ2 and IFN-λ3, or IL-29, IL-28A and IL-28B are a recently identified family of cytokines with antiviral activity. IL-28A/B and IL-29 bind to a novel heterodimeric receptor complex formed between IL-28 receptor (IL-28R) and IL-10 receptor (IL-10R2). Type I IFNs are used therapeutically in the treatment of chronic hepatitis B and C; however only ~30% of patients with he...

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Literature Corpus work
df9ccbaf-2100-52a8-bade-0a5efffdc800
DOI
10.25560/10682
Open publication

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