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Article

λ‐Interferons and the single nucleotide polymorphisms: A milestone to tailor‐made therapy for chronic hepatitis C

30 Apr 2010

Abstract excerpt

Type III interferons (IFN) (IFN-lambda1, -lambda2, -lambda3/interleukin [IL]-29, -28A, -28B) are cytokines with type I IFN-like antiviral activities. Most cells have expressed both type I and III IFN following Toll-like receptor (TLR) stimulation or viral infection, whereas the ability of cells to respond to IFN-lambda was restricted to a specific subset of cells. It was reported that signal transduction pathway...

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PMID: 20546329
DOI: 10.1111/j.1872-034x.2010.00671.x

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