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Article

IFN-Alpha receptor-1 upregulation in PBMC from HCV naïve patients carrying cc genotype. possible role of IFN-lambda.

PloS one - 1 Jan 2014

Lalle Eleonora, Bordi Licia, Caglioti Claudia, Garbuglia Anna Rosa, Castilletti Concetta, Taibi Chiara, Cristofari Francesca, Capobianchi Maria Rosaria

Abstract excerpt

BACKGROUND AND AIMS: IL-28B gene polymorphisms predict better therapeutic response and spontaneous clearance of HCV. Moreover, higher expression of IFN-lambda has been reported in patients with the rs12979860 CC favourable genotype. The study aim was to establish possible relationships between IL-28B rs12979860 genotypes and expression of IFN-alpha receptor-1 (IFNAR-1) in naïve HCV patients, and to explore the...

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Identifiers

PMID: 24691098
DOI: 10.1371/journal.pone.0093434
PMCID: PMC3972101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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