Article
Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection.
Journal of medical virology - 1 Nov 2010
Askar Eva, Ramadori Giuliano, Mihm Sabine
Abstract excerpt
Hepatitis C virus (HCV) infection affects an estimated 3% of the world's population. The natural outcome of infection and the natural course of disease are highly variable. Sensing of viral single-stranded RNA (ssRNA) by Toll-like receptor 7 (TLR7) is likely involved in early pathogen detection and host response to viral infections. This study analyzed epidemiological and clinical data from 136 patients with HCV...
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