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Article

The Role of Interferon-&#x03BB; Locus Polymorphisms in Hepatitis C and Other Infectious Diseases

1 Jan 2015

Abstract excerpt

Since its discovery in 2003, the type III interferon-λ (IFN-λ) family has been found to contribute significantly to the host response to infection. Whilst IFN-λ shares many features with type I IFN induction and signalling pathways, the tissue-specific restricted expression of its receptor, IL28RA, makes IFN-λ a major mediator of host innate immunity in tissues and organs with a high epithelial cell content. Host...

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Cytokine Signaling Pathways and Interactions
Hepatitis C virus research
Systemic Lupus Erythematosus Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25634147
DOI: 10.1159/000369902

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