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Article

Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor.

BMC medical genetics - 3 Dec 2010

Curtin Karen, Wolff Roger K, Herrick Jennifer S, Abo Ryan, Slattery Martha L

Abstract excerpt

BACKGROUND: In candidate-gene association studies of single nucleotide polymorphisms (SNPs), multilocus analyses are frequently of high dimensionality when considering haplotypes or haplotype pairs (diplotypes) and differing modes of expression. Often, while candidate genes are selected based on their biological involvement in a given pathway, little is known about the functionality of SNPs to guide association...

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Identifiers

PMID: 21129206
DOI: 10.1186/1471-2350-11-170
PMCID: PMC3006374

Genes

IKBKB
NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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