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Article

Genetic variation in inflammatory pathways is related to colorectal cancer survival.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2011

Coghill Anna E, Newcomb Polly A, Poole Elizabeth M, Hutter Carolyn M, Makar Karen W, Duggan Dave, Potter John D, Ulrich Cornelia M

Abstract excerpt

PURPOSE: Prognosis of patients with colorectal cancer (CRC) is associated with systemic inflammation, and anti-inflammatory drugs can reduce both CRC incidence and mortality. Genetic variation in proinflammatory pathways can affect an individual's CRC risk. However, few studies have investigated the prognostic importance of this genetic variation in CRC patients. EXPERIMENTAL DESIGN: We investigated the...

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Identifiers

PMID: 21976545
DOI: 10.1158/1078-0432.CCR-11-1134
PMCID: PMC3218294

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