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Article

Genetically Predicted Circulating Levels of Cytokines and the Risk of Cancer.

Frontiers in immunology - 1 Jan 2022

Song Jie, Li Aole, Qian Yu, Liu Bin, Lv Linshuoshuo, Ye Ding, Sun Xiaohui, Mao Yingying

Abstract excerpt

Background: Inflammation plays a pivotal role in the pathogenesis of cancer. Though previous studies have reported a link between several inflammatory biomarkers and risk of certain types of cancer, there is a lack of systematic investigation. Therefore, we aimed to assess the role of circulating cytokines on the risk of cancer using a two-sample Mendelian randomization (MR) approach. Method: We used genetic...

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Adipokines, Inflammation, and Metabolic Diseases
Cytokines
Genetic Associations and Epidemiology
Genome-Wide Association Study
Likelihood Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 35865545
DOI: 10.3389/fimmu.2022.886144
PMCID: PMC9294168

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