Article
Polymorphisms in inflammation pathway genes and endometrial cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2013
Delahanty Ryan J, Xiang Yong-Bing, Spurdle Amanda, Beeghly-Fadiel Alicia, Long Jirong, Thompson Deborah, Tomlinson Ian, Yu Herbert, Lambrechts Diether, Dörk Thilo, Goodman Marc T, Zheng Ying, Salvesen Helga B, Bao Ping-Ping, Amant Frederic, Beckmann Matthias W, Coenegrachts Lieve, Coosemans An, Dubrowinskaja Natalia, Dunning Alison, Runnebaum Ingo B, Easton Douglas, Ekici Arif B, Fasching Peter A, Halle Mari K, Hein Alexander, Howarth Kimberly, Gorman Maggie, Kaydarova Dylyara, Krakstad Camilla, Lose Felicity, Lu Lingeng, Lurie Galina, O'Mara Tracy, Matsuno Rayna K, Pharoah Paul, Risch Harvey, Corssen Madeleine, Trovik Jone, Turmanov Nurzhan, Wen Wanqing, Lu Wei, Cai Qiuyin, Zheng Wei, Shu Xiao-Ou
Abstract excerpt
BACKGROUND: Experimental and epidemiologic evidence have suggested that chronic inflammation may play a critical role in endometrial carcinogenesis. METHODS: To investigate this hypothesis, a two-stage study was carried out to evaluate single-nucleotide polymorphisms (SNP) in inflammatory pathway genes in association with endometrial cancer risk. In stage I, 64 candidate pathway genes were identified and 4,542...
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