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Article

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk.

International journal of cancer - 15 Dec 2010

Frank Bernd, Hoffmeister Michael, Klopp Norman, Illig Thomas, Chang-Claude Jenny, Brenner Hermann

Abstract excerpt

Chronic inflammation is an established risk factor for colorectal cancer (CRC), and polymorphisms in genes regulating inflammatory processes appear to alter the risk for neoplasia and the efficacy of nonsteroidal anti-inflammatory drugs in CRC chemoprevention. We examined the association between selected inflammation gene polymorphisms and CRC risk. In a large population-based case-control study with 1,795 CRC...

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Source

Identifiers

PMID: 21351261
DOI: 10.1002/ijc.25299

Genes

PTGS1
UBD
PRODH

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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