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Article

Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients.

Oncology reports - 1 Jan 2011

Kim Jong Woo, Park Hye Mi, Choi Young-Kook, Chong So Young, Oh Doyeun, Kim Nam Keun

Abstract excerpt

Aberrant methylation of promoter regions associated with gene silencing is one of the major mechanisms underlying the inactivation of tumor suppressor genes in carcinogenesis. Previous studies have proposed that methylated DNA from tumor cells is released into the circulation and might be widely used as a marker for non-invasive tumor detection. Catalytic activities of folate metabolism-related enzymes and...

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Source

Identifiers

PMID: 21109973

Genes

MTHFR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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