Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization.

doi:10.1016/0042-6822(90)90228-j

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Article

Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization.

Virology - 1 May 1990

Venkatesh L K, Mohammed S, Chinnadurai G

Abstract excerpt

The rev gene of human immunodeficiency virus type 1 (HIV-1) encodes a 116 amino acid nuclear regulatory protein (Rev) that increases the cytoplasmic expression of viral mRNAs containing the Rev response element (RRE) and coding for the structural proteins, Gag and Env. To identify the functional...

Topics

Amino Acid Sequence
Base Sequence
Chimera
Chloramphenicol O-Acetyltransferase
Genes, Viral
Genes, rev
HIV-1
HeLa Cells
Humans
Molecular Sequence Data
Mutation
Transcriptional Activation
Transfection
beta-Galactosidase

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