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Article

Probing the structure of the HIV-1 Rev trans-activator protein by functional analysis.

Protein engineering - 1 Feb 1997

Thomas S L, Hauber J, Casari G

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) encodes a trans-acting regulatory protein, termed Rev, which is critically required for virus replication. Rev is a sequence-specific RNA binding protein which mediates the nuclear export of unspliced and incompletely spliced viral mRNAs encoding the viral structural proteins. While CD and fluorescence measurements have provided several possible structural models of...

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PMID: 9089809
DOI: 10.1093/protein/10.2.103

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Probing the structure of the HIV-1 Rev trans-activator protein by functional analysis.PMID 9089809Read ↗

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