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Article

Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 1 is dependent on the activation domain of the protein.

Experimental cell research - 1 Mar 1995

Wolff B, Cohen G, Hauber J, Meshcheryakova D, Rabeck C

Abstract excerpt

The human immunodeficiency virus type 1 (HIV-1) regulatory protein Rev, which is required for the cytoplasmic expression of unspliced and incompletely spliced viral mRNAs, is located predominantly in the nucleolus. In this study, we show that Rev translocates from the nucleolus to the cytoplasm in HeLa and COS cells transfected with Rev under conditions where rRNA synthesis is inhibited (e.g., with actinomycin...

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Identifiers

PMID: 7867718
DOI: 10.1006/excr.1995.1060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 1 is dependent on the activation domain of the protein.PMID 7867718Read ↗

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Rev regulates translation of human immunodeficiency virus type 1 RNAs.Semantic proximity Read ↗

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