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Article

Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

1 Nov 1990

Abstract excerpt

The expression of certain mRNAs from human immunodeficiency virus type 1 (HIV-1) is controlled by the viral transactivator Rev, a nucleolar protein that binds a cis-acting element in these mRNAs. Rev is encoded by two viral exons that specify amino acids 1 to 26 and 27 to 116, respectively. Earlier studies have mapped essential regions of the protein that are encoded in the second exon. By further mutational...

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PMID: 2120472
DOI: 10.1128/jvi.64.11.5360-5366.1990

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Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminusPMID 2120472Read ↗

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