Article
Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function.
Journal of virology - 1 Feb 1990
Cochrane A W, Perkins A, Rosen C A
Abstract excerpt
The human immunodeficiency virus rev gene product regulates the expression of viral structural genes. It was recently shown that Rev regulates the export of viral structural mRNAs from the nucleus to the cytoplasm. Analysis of Rev subcellular localization reveals marked accumulation in the nucleo...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Cell Nucleus
- Gene Expression
- Gene Expression Regulation, Viral
- Gene Products, rev
- Genes, Viral
- HIV
- Molecular Sequence Data
- Mutation
- Plasmids
- Recombinant Fusion Proteins
- Trans-Activators
- Viral Structural Proteins
- rev Gene Products, Human Immunodeficiency Virus