Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Minimal Rev-response element for type 1 human immunodeficiency virus.

Journal of virology - 1 Apr 1991

Huang X J, Hope T J, Bond B L, McDonald D, Grahl K, Parslow T G

Abstract excerpt

Rev protein regulates nuclear export of viral mRNAs that contain a 240-base RNA sequence termed the Rev-response element (RRE). We demonstrate that an 88-base truncated RRE encompassing a known Rev binding site can mediate Rev responsiveness in vivo. Two tandem copies of this mutant function as efficiently as the full-length RRE.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Binding Sites
Share to HIV-1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Nucleic Acid Conformation

Share to Repetitive Sequences, Nucleic Acid

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 2002556
DOI: 10.1128/JVI.65.4.2131-2134.1991
PMCID: PMC240087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Minimal Rev-response element for type 1 human immunodeficiency virus.PMID 2002556Read ↗

Mutational analysis of the HIV-1 Rev protein and its target sequence, the Rev responsive element.Semantic proximity Read ↗

Human immunodeficiency virus rev protein recognizes a target sequence in rev-responsive element RNA within the context of RNA secondary structureSemantic proximity Read ↗

Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein.Semantic proximity Read ↗

Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.Semantic proximity Read ↗

Secondary structure is the major determinant for interaction of HIV rev protein with RNA.Semantic proximity Read ↗

Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminusSemantic proximity Read ↗

HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.Semantic proximity Read ↗

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication.Semantic proximity Read ↗

Mutational definition of the human immunodeficiency virus type 1 Rev activation domainSemantic proximity Read ↗

Mutation-driven RRE stem-loop II conformational change induces HIV-1 nuclear export dysfunction.Semantic proximity Read ↗

Mutational analysis of functional domains in the HIV-1 Rev trans-regulatory protein.Semantic proximity Read ↗

Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.