Minimal Rev-response element for type 1 human immunodeficiency virus.

Abstract excerpt

Rev protein regulates nuclear export of viral mRNAs that contain a 240-base RNA sequence termed the Rev-response element (RRE). We demonstrate that an 88-base truncated RRE encompassing a known Rev binding site can mediate Rev responsiveness in vivo. Two tandem copies of this mutant function as e...

Topics

• Base Sequence
• Binding Sites
• Genes, env
• HIV-1
• Molecular Sequence Data
• Mutation
• Nucleic Acid Conformation
• RNA, Messenger
• Repetitive Sequences, Nucleic Acid