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Article

Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990

Hope T J, Huang X J, McDonald D, Parslow T G

Abstract excerpt

The human immunodeficiency virus type 1 (HIV-1) transactivator Rev is a nuclear protein that regulates expression of certain HIV-1 transcripts by binding to an RNA target element (the RRE) present in these transcripts. A short arginine-rich sequence in Rev contains the signals required to direct this protein into nuclei, where it associates preferentially with nucleoli. We created a steroid-inducible...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2217212
DOI: 10.1073/pnas.87.19.7787
PMCID: PMC54833

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Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif.PMID 2217212Read ↗

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Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminusSemantic proximity Read ↗

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.Semantic proximity Read ↗

Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization.Semantic proximity Read ↗

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Human immunodeficiency virus rev protein recognizes a target sequence in rev-responsive element RNA within the context of RNA secondary structureSemantic proximity Read ↗

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