Article
Point mutations of c-ras genes in human bladder cancer and kidney cancer.
Japanese journal of cancer research : Gann - 1 Jan 1990
Nagata Y, Abe M, Kobayashi K, Saiki S, Kotake T, Yoshikawa K, Ueda R, Nakayama E, Shiku H
Abstract excerpt
Point mutations of c-ras genes at codons 12, 13 and 61 were analyzed in 26 cases of bladder cancer and 16 cases of kidney cancer. DNA prepared from either frozen tissues or 10% formalin-fixed, paraffin-embedded tissues were amplified by means of polymerase chain reaction methods, and mutations we...
Topics
- Aged
- Base Sequence
- Codon
- DNA, Neoplasm
- Female
- Humans
- Kidney Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)
- Urinary Bladder Neoplasms